Despite significant advances in the past 50 years, cardiovascular disease (CVD) remains the leading cause of death in Australia and most of the developed world. Identification and management of risk factors has led to a significant decrease in the incidence of fatal and non-fatal CVD, however approximately 1 in 5 people who suffer a heart attack have no standard modifiable risk factors.

The goal of this project is to employ innovative scientific methods to investigate how genes, proteins and immune cells interact to either contribute to or protect against the development of CVD.

The results of this project will identify new mechanisms and pathways driving the development of CVD. Findings from this project may be used to guide new methods for screening and prevention of CVD, as well as identify novel therapeutic targets.